Lyme Disease Journal Articles
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Lyme disease, caused by spirochete Borrelia burgdorferi, is the most common vector-borne disease in the United States.The clinical presentation varies depending on the stage of the illness: early disease includes erthyma migrans, early disseminated disease includes multiple erythema migrans, meningitis, cranial nerve palsies and carditis; late disease is primarily arthritis.
Purpose of review: Lyme disease is an important, vector-borne infection found throughout the temperate Northern hemisphere. The disease causes rash, acute systemic illness, and in some untreated patients, inflammatory arthritis. This review examines the emergence, clinical features and management of early Lyme disease and Lyme arthritis.
THE CHRONIC LYME DISEASE CONTROVERSY. Chronic Lyme disease (CLD) is a poorly defined term that describes the attribution of various atypical syndromes to protracted Borrelia burgdorferi infection. These syndromes are atypical for Lyme disease in their lack of the objective clinical abnormalities that are well-recognized in Lyme disease and, in many cases, the …
Lyme disease is commonly categorized into two main stages: early stage, where infection is localized (e.g., an expanding erythema migrans lesion), or disseminated stage, where infection has spread beyond the initial bite location [3–5]. Untreated, Lyme disease typically progresses from a localized skin infection, often with systemic non ...
The Review article by Halperin et al1 concerning Lyme disease “misconceptions” is the latest in a series of Lyme denialist attacks by members and supporters of the Infectious Diseases Society of America (IDSA). 1,2,3,4 This series of copycat opinion pieces is disturbing from both a scientific and political perspective because the articles frame the complex debate over chronic Lyme …
Since the last review of Lyme disease in the Journal 12 years ago, 4 the number of scientific articles about this entity has increased substantially. …
Lyme disease is an important, vector-borne infection found throughout the temperate Northern hemisphere. The disease causes rash, acute systemic illness, and in some untreated patients, inflammatory arthritis. This review examines the emergence, clinical features and management of early Lyme disease and Lyme arthritis. Recent findings
After Lyme borrelia are deposited in the skin by the bite of an infected Ixodes tick, an infection is typically established at that site, which causes the characteristic skin lesion, erythema migrans ().Erythema migrans is the most common clinical manifestation of Lyme disease in the United States and Europe, occurring in > 80% of patients in both geographic …
Other characteristic manifestations of early disseminated disease include Lyme neuroborreliosis, Lyme carditis, fever, myalgias, arthralgias, headache, and/or fatigue. 8 Neurologic manifestations of Lyme neuroborreliosis include meningitis, facial palsy, headache, meningismus, numbness, and tingling. 8 Lyme carditis typically presents as atrioventricular nodal dysfunction with symptoms …
(Some journals put their articles behind hefty paywalls, making them largely inaccessible to the Lyme patient community.) Healthcare’s special issue on Lyme Disease and Related Tick-borne Infections includes such diverse topics as a new test for tick-borne relapsing fever, Lyme-related psychiatric illness, and problems faced by families with Lyme disease.
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