Lupus Erythematosus Journal

Lupus Erythematosus Journal

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Systemic Lupus Erythematosus: Diagnosis and Clinical ...

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6310637/
    Systemic lupus erythematosus (SLE) is a worldwide chronic autoimmune disease which may affect every organ and tissue. Genetic predisposition, environmental triggers, and the hormonal milieu, interplay in disease development and activity. Clinical manifestations and the pattern of organ involvement are widely heterogenous, reflecting the complex mosaic of disrupted …

The Diagnosis and Treatment of Systemic Lupus …

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4558874/
    Systemic lupus erythematosus (SLE) is an autoimmune disease with a prevalence of 36.7/100 000 in Germany and a female/male ratio of 4:1. The clinical course is variable, with a broad spectrum of organ manifestations; lupus nephritis …

The Pathogenesis of Systemic Lupus Erythematosus – …

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3508331/
    Systemic lupus erythematosus (SLE, or lupus) is a systemic autoimmune disease with multiorgan inflammation. SLE is characterized by production of pathogenic autoantibodies directed against nucleic acids and their binding proteins, reflecting a global loss of self-tolerance (reviewed in [1]). The loss of tolerance with subsequent immune dysregulation is a consequence of genetic …

What's New in the Treatment of Systemic Lupus …

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7973110/
    Systemic lupus erythematosus (SLE) is an astonishing heterogeneous multisystem autoimmune disease with a quite unpredictable outcome. Patients suffering from SLE are typically treated with corticosteroids and immunosuppressive agents . An eminent direct or indirect target of novel therapeutic approaches has been the lupus B cell (2–4). Among ...

Lupus: SAGE Journals

    https://journals.sagepub.com/home/lup
    About this journal. The only fully peer reviewed international journal devoted exclusively to lupus (and related disease) research. Lupus includes the most promising new clinical and laboratory-based studies from leading specialists in all lupus-related disciplines. Invaluable reading, with extended coverage, lupus-related disciplines include: Rheumatology, …

Mechanisms of Disease Systemic Lupus …

    https://www.nejm.org/doi/pdf/10.1056/NEJMra071297
    Systemic lupus erythematosus has many guises, but the unifying feature is the presence of antibodies against double-stranded DNA in almost all …

Epstein–Barr Virus in Salivary Samples from Systemic …

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8584540/
    1. Introduction. Systemic lupus erythematosus (SLE) is a chronic autoimmune rheumatic disease with unknown and unclear etiopathogenesis, with various clinical presentations, some of which are potentially life threatening [1,2,3].SLE is characterized by B and T cell dysregulation [] and autoantibody production leading to the potential attack of any organ system [].

Trial of Anifrolumab in Active Systemic Lupus …

    https://www.nejm.org/doi/full/10.1056/NEJMoa1912196
    Anifrolumab for Systemic Lupus Erythematosus. Systemic lupus erythematosus (SLE) is associated with clinical burden for the patient and organ damage. 1 One disease-specific therapy, belimumab, has ...

Juvenile Systemic Lupus Erythematosus Presenting with ...

    https://www.hindawi.com/journals/crirh/2021/5868655/
    We present a case of a previously healthy adolescent female who developed severe oral mucositis and acute esophagitis as her presenting symptoms of juvenile systemic lupus erythematosus. Mucositis involving the lips is infrequently reported in systemic lupus erythematosus, and to our knowledge, this is the first reported case of acute, non-infectious …

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